Cursed Skull

Due to their vulnerability to bludgeoning damage, they are easy to destroy from a safe distance.

Cursed Skulls are found in the upper floors of Lady Jannath's Estate. They cast Thunderwave when a player character is nearby, making them difficult to evade. The skulls ignore Invisibility and similar effects.

Strategy

Cursed skulls are difficult to approach as they will cast Thunderwave against nearby creatures. Therefore it's advised to simply throw a bludgeoning weapon at them which has the "thrown" trait. A simple Light Hammer thrown by a character with decent Strength is sufficient to kill a skull in one blow. Eldritch Blast is also a good option since the skulls are also vulnerable to force damage.

Alternatively, casting Remove Curse will remove the  Cursed Skull status from a skull, preventing it from casting Thunderwave. However, this requires being within range of the skull's attack. One method of applying remove curse is using Misty Step to blink to a location outside of the skull's line of sight, then casting from behind or from the side if you position yourself carefully.

Casting the ritual spell Silence on a skull will entirely neutralise its thunderwave attack.

Ne'er Misser with a character that has high enough Dexterity can also kill it in one blow without going near it.