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The Sharran Sanctuary is a location found under Reithwin Town in the Shadow-Cursed Lands in Act Two.
Accessing the Sharran Sanctuary
In Reithwin Town, north of the 
Moonrise Towers waypoint, find the statue of Ketheric Thorm X: -152 Y: -30 and interact with the plaques in the following order: north, west, east.
This opens a hidden staircase on the south side of the statue that leads down into the sanctuary.
The Dark Lady's ritual
Each of the three statues provides a unique Shar blessing until the next Long Rest:
(+5 to Charisma) - Center statue- (+5 to Wisdom) - South-eastern statue (on the right as viewed from the center statue)
- (+5 to Intelligence) - North-eastern statue (on the left as viewed from the center statue)
A DC 14 
Saving throw for the corresponding Ability is required at each of the statues in order to receive the Dark Lady's blessing(s). Each blessing may only be obtained once. As a cleric of Shar, Shadowheart can bypass the saving throw using a unique dialogue option with guaranteed success.
Succeeding all three saving throws will open a door to a hidden chamber where a sacrificial ritual can be completed. (It is not necessary for all three saving throws to be made by the same character.) Completing this ritual will reveal the scrolls and potions listed below.
Stealing the Ritual Dagger of Shar, even after the ritual is successfully completed, will trigger combat against a Charismatic Sentinel, a Wise Sentinel and an Intelligent Sentinel. This combat can also be triggered by attacking the statues outside the hidden chamber.
Notable loot
Notable items obtained in this location, whether looted, purchased, or obtained as a quest reward:
- In the hidden ritual chamber:
Ritual Dagger of Shar (taking the dagger spawns a Charismatic Sentinel, Intelligent Sentinel and Wise Sentinel, and yields disapproval from Shadowheart)
- Additional loot revealed by completing the ritual:
